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Summary: Glutathione is key to electron flow Virtually every substance that enters the body through respiration, absorption, or ingestion will ultimately be broken down, or digested, into components that are antioxidant or pro-oxidant
See Supplemental Methods for detailed experimental procedures
For instance, HMGB1 not only participates in regulating the production of inflammatory mediators but also promotes the entry of lipopolysaccharides into cells, thereby triggering pyroptosis, which plays a crucial role in sepsis
doi: 10.1016/s0006-8993(98)00319-9
10.1371/journal.pone.0030200 PLoS One 51 SilveiraC
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