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Semaglutide is a GLP-1 receptor agonist that delays gastric emptying, suppresses hypothalamic hunger signalling, and produces mean body weight reductions of 14.9% over 68 weeks in Phase III trials

Results showed that a twice daily IGF-1 dose of 120mcg/kg produced almost identical effects as that of a twice daily 80mcg/kg dose [18]

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doi: 10.1016/j.ejcb.2017.03.004 185 ZhengCZhouMSunJXiongHPengPGuZet al