Phase II Detoxification: It is a key substrate for the enzyme Glutathione S-transferase (GST), which binds to toxins and xenobiotics (foreign chemical substances), rendering them water-soluble for excretion
This protects the peptide structure
It is also a very popular target for site-directed labeling experiments to investigate biomolecular structure and dynamics
Ziegler D, Ametov A, Barinov A, Dyck PJ, Gurieva I, Low PA, Munzel U, Yakhno N, Raz I, Novosadova M, Maus J
Figure 7 4 Discussion Mounting evidence indicates the important role of the complex interaction between metabolic networks and the immune system in modulating autoimmunity responses ( To date, the majority of metabolomic studies on MS have primarily focused on Caucasian populations ( In the current study, we found that the metabolic profile in the peripheral blood of Chinese patients with MS significantly differed from that of healthy controls