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Intratumor heterogeneity and cell secretome promote chemotherapy resistance and progression of colorectal cancer
Staying well hydrated is important, especially if you are experiencing diarrhea or vomiting, since these can lead to dehydration
As an additional safety measure, all patients in Europe had additional laboratory data collection at weeks 4, 8, 12 and 16, with creatinine and UACR tests performed at the central laboratory, and the CKD-EPI 2021 equation used for eGFR
In some cases, patients may experience moderate discomfort, which might require treatment with over-the-counter or prescription creams and ointments