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10.1016/j.jconrel.2021.11.028 166 ZhaoR.LiuJ.LiZ.ZhangW.WangF.ZhangB

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The key finding was that plasma concentrations in patients taking 8 mg of retatrutide (approximately 182 nanomolar) exceeded the effective concentrations observed in the laboratory, suggesting these cardiac effects are clinically relevant at therapeutic doses

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