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Nature 2010, 466: 779-U718

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Moreover, PBPK models can incorporate physiological, preclinical, and clinical data into the model to predict drug exposure during pregnancy [140,141]

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10.1152/ajpendo.2001.280.1.E75 179 LiH.WitteK.AugustM.BrauschI.Godtel-ArmbrustU.HabermeierA.et al (2006)

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Tips to Manage GLP-1 Constipation: Hydration is Key: Ensure you're drinking an adequate amount of water throughout the day

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Mechanism understanding helps troubleshooting non-responders, switching to peptides targeting different pathways potentially more relevant for specific individual pathophysiology

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