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Mental Health and Behavioral Changes Some patients report: Depression Mood changes Suicidal thoughts While not yet proven as a direct effect, the FDA advises close monitoring of mental health while on GLP-1 drugs

[62] However, the mechanisms through which they exert their effects are not fully understood

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This harmful effect was not limited to the summer season, as it continued until autumn, indicating a carry-over effect caused by heat stress during the summer

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