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The role of the renin-angiotensin system (RAS) in hypertension and emotional disorders is well established

The dietary phase 2 protein inducer sulforaphane can normalize the kidney epigenome and improve blood pressure in hypertensive rats

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Nan and colleagues demonstrated that treatment with rosiglitazone, a ligand activating PPAR, prevents the development of fibrosing steatohepatitis induced by a methionine-choline deficiency (MCD) diet in C57BL6/J mice (215)