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Objectively measured outcomes, such as degree of curvature or plaque characteristics or penile dimensions or ED, are critically important to establish that a therapy is effective in reducing these manifestations of PD

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Typical starting doses include: Semaglutide (Wegovy): 0.25 mg weekly Tirzepatide (Zepbound): 2.5 mg weekly These starting doses were studied in programs such as the STEP and SURMOUNT trials and were gradually increased to achieve validated metabolic outcomes

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