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Prespecified and integrated subgroup analyses from the RECONNECT trials
Unlike systemic immunosuppression, this technique uses direct lymph node delivery of PLGA microparticles encapsulating MOG 35-55 peptide and rapamycin, promoting antigen-specific tolerance with minimal systemic exposure ( Figure 5B ) (201)
Oral glutathione has poor bioavailability because stomach acid and digestive enzymes break it down before intestinal absorption
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