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For treatment of primary systemic carnitine deficiency, a genetic impairment of normal biosynthesis or utilization of levocarnitine from dietary sources, or for the treatment of secondary carnitine deficiency resulting from an inborn error of metabolism such as glutaric aciduria II, methyl malonic aciduria, propionic acidemia, and medium chain fatty acylCoA dehydrogenase deficiency
At 96 h post-dosing, 20.022% (17.3% in urine, 0.752% in bile, and 1.97% in feces) and 14.763% (12.5% in urine, 0.623% in bile, and 1.64% in feces) of Deg-AZM were excreted from male and female rats, respectively
At the commencement of this study, the FDA only published data for the first quarter of 2023