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While directly measuring neuroprotection in living patients is technically unfeasible, alternative strategies, such as monitoring pro-inflammatory markers or neuroprotective cytokines in the plasma of patients receiving istradefylline, could offer valuable mechanistic insights and serve as surrogate indicators of therapeutic activity [485]
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Interestingly, the blood Hcy of the same patients was normal (11.7 2.9 Mol) suggesting the occurrence of a follicle-specific impairment of Hcy metabolism in PCOS and a main role of Hcy in PCOS subfertility also in women with normal Hcy blood values
Int J Radiat Oncol Biol Phys 64(3):692-699, 2006
The worst performing method was Decision Trees with an accuracy of 0.675, precision of 0.571, recall of 0.599, F1 score of 0.570 and ROC-AUC of 0.654 Conclusion: Using machine learning methods, we were able to predict the presence of fatty liver disease with high accuracy, precision, and recall
