Lysosomal dysfunction might play an important role in the development of various diseases, including tumors 14,15,16 , neurodegenerative diseases 17,18,19 , inflammatory diseases 20,21,22 , and cardiovascular diseases 23,24,25 (Table 1)
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HOMA-IR, homeostatic model assessment of insulin resistance
Reversal of apoptosis induced by H 2 O 2 in Prx II-knockdown HaCaT cells by BAPTA-AM and 2-APB treatment Treatment with BAPTA-AM, a selective Ca 2+ chelating agent significantly reversed apoptosis in Prx II-knockdown HaCaT cells induced by H 2 O 2 treatment (Fig
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