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By integrating advanced fabrication technologies such as 3D printing and injectable in situ -forming hydrogels, the macroscopic morphology and microstructure of the metal-based nanozyme-hydrogel composite system can be tailored to meet the complex demands of various clinical scenarios (such as injectable filling, microsphere delivery, customized implantation, and intelligent dressings) [24]

10.1111/j.1749-6632.1999.tb08644.x 123 SelivanovaO.BriegerJ.HeinrichU

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After purification, the tag can be cleaved from the fusion protein at appropriately engineered molecular sites, typically in a buffer exchange step