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ROS-induced DNA damage, genomic instability, and altered signaling pathways have all been implicated in the initiation and promotion of lung carcinogenesis [15,16,17]

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Acknowledgments We would like to acknowledge the financial support from the Ministry of Education in the Long Term Research Grant Scheme (LRGS/BU/2012/UKM-UKM/K/01) and also the direct and indirect input from the research team toward the study

Those with psoriasis have a markedly increased risk of developing other major inflammatory disorders, particularly: cardiovascular disease diabetes metabolic syndrome stroke Note: This link between psoriasis and systemic health is underscored by a 5-year diminished life expectancy among those with the disease, largely attributable to increased cardiovascular disease risk

Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide