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Statistical analysis Dierences among all UA treated groups were analyzed with one-way ANOVA, Tukeys multiple comparisons test on GraphPad Prism 6 soware

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Contamination and Oxidation from Poor Technique Every time a needle punctures the stopper of a reconstituted vial, there is a small opportunity for contamination

These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations