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"They're not based on human models." In an email to CBC News, he stated he was candid with his patients about the current research regarding BPC-157

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BPC-157 has demonstrated effects on platelet function and thrombus formation in rat models, reducing excessive thrombosis through NO-pathway modulation 16

Consultation and area assessment

Two possibilities explain the animal oral data: Local action without systemic absorption: BPC-157 at high luminal concentrations acts directly on GI epithelium, submucosal vessels, and enteric neurons without requiring absorption into the bloodstream