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1.1.3 Relationship between hyperuricemia and other diseases Hyperuricemia is increasingly recognized as a significant health concern, often dubbed the fourth high, alongside elevated blood sugar, high blood lipids, and hypertension

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MacPherson JC, Comhair SA, Erzurum SC, Klein DF, Lipscomb MF, et al: Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species