When choline balance is insufficient to meet demands, flows of choline-related molecules through these pathways are regulated in manners that attempt to restore the needed levels of choline and its metabolites, particularly in the liver and brain
Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans
While numerous probes have shown high sensitivity toward GSH, their selectivity over other thiols such as cysteine and homocysteine remain a major limitation
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