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Antioxidants 14 (2), 144

This is because the focus of a diet is not on maximising fat burning in the muscle cells, but on generally increasing fat burning in the long term in order to break down fat deposits

GLP-1 weight loss injections work by mimicking naturally occurring hormones that regulate appetite and blood sugar, reducing hunger while improving metabolic function

DOI: Published online: May 1, 2025 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea 2 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Corresponding author: Jae Hyun Bae Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

55-58 Preliminary results of the Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE) study, a long-term multicenter trial on the effects of calorie-restricted diets in healthy overweight volunteers, 59 showed moderate calorie restriction can reduce several cardiovascular risk factors (LDL cholesterol, triglycerides, blood pressure, and C-reactive protein)