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Most vitamin C and glutathione formulations are best applied to clean skin in the morning, followed by moisturizer and always finished with a broad-spectrum sunscreen, since antioxidants work best as part of a layered defense rather than a replacement for sun protection

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Both reactive oxygen species and antioxidants are required for a healthy functioning system, and a tip in the balance towards increased oxidative stress has thus been linked to the development of depression (Correia et al

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