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Circulating TMAO has been identified as a risk factor for various chronic conditions, including kidney disease, type 2 diabetes (T2DM), musculoskeletal disorders, and cancer (162)

2a, b) confirmed the assumption that selenium has the property that inhibits the growth of microorganisms

Glucocorticoids, secreted primarily by the adrenal glands, are important clinical drugs used to control pain and reduce inflammation in autoimmune diseases, neurological injury, cancer, and more

Prolonged angiogenic signaling may encourage unwanted vascular growth in tissues where balance is key (think: cancer cells use these same pathways to grow we want to avoid that) , especially if theres a history of cellular overgrowth or injury-prone tissue