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The STEP 1 trial, published in the New England Journal of Medicine, showed that this sustained caloric reduction led to an average weight loss of 14.9% of body weight over 68 weeks

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Conclusions : Quinone products and ONOO-/O2- are involved in the long-term DA-mediated inactivation of complex I and complex IV References : Khan et al

Eating adequate protein may help: Reduce hunger between meals Support stable blood sugar Reduce late-night snacking Maintain muscle while losing fat Keep you feeling satisfied for longer Aim to include around 25-35 grams of quality protein at every main meal