While urinary excretion of VC metabolites (oxalate, threonate) maintains systemic balance, prolonged deficiency ( ShacterEet alAscorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
My personal view is that this is a theoretical risk, and it will be low on my list of safety warnings for people in whom I initiate tirzepatide
Finally, we map out follow-ups: repeat labs, DEXA or bioimpedance checks, and symptom tracking that prioritize metabolic resilience, strength, and quality of life over scale-only wins
A thorough discussion with a healthcare provider is essential to determine if they are an appropriate option
Sources : Fatty fish like salmon, mackerel, and sardines (rich in omega-3 fatty acids) Walnuts, flaxseeds, and chia seeds Soybean oil and sunflower oil Benefits : Brain Health : Omega-3 fatty acids, a subtype of PUFAs, are essential for cognitive function and reducing the risk of neurological diseases like Alzheimer's