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Histopathology of penile melanosis or lentiginosis is characterized by an increase in melanin in the basal layer, a discrete melanocytic hyperplasia without nest formation, as well as an epithelial hyperplasia and melanophages in the dermis[1-5]

GLP-1 therapies are marking the start of a new generation of targeted medications that reshape how we approach metabolic health

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As always, we encourage readers to consider funding sources for primary studies when evaluating the evidence and to discuss any concerns with their healthcare team

In contrast, fulguration of Hunner lesions was designated a Recommendation (based Grade C evidence) because little to no uncertainty existed regarding the fact that benefits (large and sustained treatment effects) clearly outweighed risks/burdens