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Mechanistically, they activate Nrf2 and block ubiquitin-mediated GPX4 degradation, thereby inhibiting ferroptosis and alleviating cartilage erosion, pain, and gait abnormalities in DMM-induced OA (192)

Also, this technique is appropriate for investigating the direct interaction between two purified proteins

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The CYC1 promoter was selected for this as in YEPD culture it supports similar, only slightly stronger expression than pGSH1 (but much stronger expression than pGAP1 ), according to transcriptomic data from YEPD culture [42]