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This represents the most important distinction from both mechanistic and research perspectives

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Under physiological conditions, GSH quenches oxidizing substances (such as reactive hydroxyl free radicals, peroxynitrite, and H 2 O 2 ) directly or reduces hydrogen peroxide (or lipid peroxide (lipid-OOH)) to water (or the corresponding lipid alcohol (lipid-OH)) under the catalysis of GPX (summarized in Fig

This substitution may increase the half-life of the peptide by protecting it from enzymatic cleavage and degradation

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