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This movement renders the upper halves of TM1, TM2 and TM7 outward by 6.0 , 4.9 and 6.6 , measured at the C atoms of E139 1.34b , K202 2.72b and T378 7.33b (class B1 GPCR numbering in superscript), respectively ( Fig

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Highlighting its importance, dysregulation of ERAD often results in devastating diseases

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