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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Browning KN, Verheijden S, Boeckxstaens GE

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In a portal hypertension model, FMT enriched butyrate-producing bacteria, and the resulting butyrate activated the PI3K/Akt/eNOS signaling pathway by inhibiting HDAC3 activity in liver sinusoidal endothelial cells, increasing nitric oxide production and thereby reducing intrahepatic vascular resistance