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Multiple cell types, including fibroblasts, endothelial cells, and keratinocytes, participate in wound repair by forming new tissues to fill defects, such as neovessels, ECM components, and granulation tissue, ultimately achieving epithelialization [27,28,29]

A., Kamensky, A

These studies have shown that NOR is an effective monomer drug for the treatment of RA, which can play a role by anti-inflammation, immune regulation, promoting synovial cell apoptosis, inhibiting osteoclast differentiation and synovial angiogenesis, and regulating lipid metabolism

Furthermore, inflammatory cells attract proangiogenic leukocyte subsets and produce growth factors, which encourage angiogenesis and support tumor development

Ruscio AM, Stein DJ, Chiu WT, Kessler RC