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Reddys Laboratories, Apotex)

Juarez-Fernandez et al., 2021)

However, it is worth noting these improvements may reflect the physiologic consequences of rapid weight loss rather than reversal of underlying disease mechanisms, and whether such changes would persist without definitive obesity treatment is unknown

29 In keeping with this, the GLP-1 mimetics exendin-4 and liraglutide improve trabecular bone microarchitecture and reduce osteoclast activity in ovariectomised (OVX) mice

However, most herbal compounds lack the clinical evidence and potency of FDA-regulated prescription therapies, which have demonstrated weight loss of 15-22% in clinical trials