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Chronic obstructive pulmonary disease: After two months of therapy, open-label research of 1,392 patients discovered that NAC reduced the viscosity of expectorated phlegm, reduced cough intensity, and increased ease of expectoration in 80%, 74%, and 71% of patients, respectively [43]

The reason for the greater increase in our study is presumably that excessive L-carnitine is excreted into the urine in mice, while in the medaka model, the compound was dissolved in the water in the tank, which allowed medakas to maintain higher L-carnitine levels