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When the benefit outweighs the side effect, and when it might not For most patients, the metabolic benefits of GLP-1 therapy, including improved cardiovascular risk factors, better insulin sensitivity, reduced visceral fat, and meaningful weight loss, far outweigh a temporary or modest change in libido

Conclusion: We show that a variant in PNPLA3 drives steatotic liver disease progression in this sample

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These medications help regulate appetite and satiety, creating a more supportive biological environment for weight loss, but long-term success still depends on building habits that can be maintained over time

Research shows that rapid weight loss or very low calorie intake can reduce milk supply