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This leads to reduced clearance of A and its accumulation in the brain

The most effective drug is the calcium channel blocker amlodipine (0.625 to 1.25 mg/cat orally every 12 to 24 hours).15 If improvement doesn't occur after 48 to 72 hours, increase the dose.15 If you reach the dose's upper range without controlling blood pressure adequately, add an ACE inhibitor such as benazepril (2.5 mg/cat orally every 24 hours for cats weighing 2.5 to 5 kg)