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Because of this massive energy demand, the brain is packed with mitochondria and highly susceptible to oxidative stress
Sublingual formulations: Sublingual GLP-1 preparations typically need refrigeration, though some stable formulations may allow short-term room temperature storage
The dual- and tri-agonist approach is attracting attention due to Mounjaros success, and recent data for one of Lillys pipeline products retarutide are promising
A randomized controlled trial comparing empagliflozin with metformin demonstrated that SGLT2 inhibition achieved superior improvements in anthropometric parameters and body composition [35]
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