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Low serum B12 concentrations and elevated methylmalonic acid [38] are not consistently correlated with the presence or severity of polyneuropathy or the clinical response to B12 treatment [39]

However, the company stated that its latest trials still met key goals related to efficacy and tolerability

For more in-depth information, you can visit the clinical trial results at The New England Journal of Medicine and an overview of its mechanisms at NCBI.

If you maintain your current weight during the initiation period, you are on track

These deaths have been associated with maternal dietary deficiency of vitamin E and/or selenium