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For instance, in prokaryotes, GSR is found in the periplasm [13,14], while in eukaryotes, it is found in the mitochondria, cytosol, endoplasmic reticulum and nucleus [1517]

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These medications are FDA-approved primarily for the treatment of type 2 diabetes mellitus, with some formulations also approved for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity