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Considerations: May be appropriate for individuals with emotional eating or cravings, but carries risks such as nausea, headache, and may not be suitable for people with a history of seizures

Patient Vigilance Remains Paramount: In mitigating these risks

[DOI] [PubMed] [Google Scholar] 57.A Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease (FLOW) [(accessed on 14 April 2023)]

Clinical practice shows that some individuals reach their weight loss and metabolic goals at 1.01.7 mg and experience diminishing returns or increased side effects at higher doses

While the U.S faced a shortage of semaglutide in 2024 and early 2025, pharmacies could legally produce bulk compounded versions of the drug because shortages trigger temporary allowances under federal law to fulfill patient demand