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Directions: Adults 1 capsule daily with a meal with plenty of water

107-109 Some evidence suggests that long-term berberine use, especially at high doses, may impair particular aspects of cellular metabolism in specific types of cells

3.3 Activation of inflammatory pathways ROS can disrupt mitochondrial lipid membrane integrity and lead to mPTP abnormalities, resulting in oxidative damage and leakage of mtDNA (137, 138)

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It also increases exercise performance as it uses fat for energy, which leads to better energy production and expenditure during any physical activity, leading to a greater weight drop