And were only beginning to understand why
Novo Nordisk, Pfizer and other big pharma companies have just taken [the hormone] GLP-1 itself, and spent 20 years stabilising the peptide, making it druggable, so its not broken down [in the body], explains John Unitt, vice president of immunology and inflammation drug discovery at Sygnature Discovery in Nottinghamshire, UK, and a GPCR drug discovery expert
Popular GLP-1 Medications The GLP-1 landscape includes several widely prescribed options: Semaglutide (Ozempic, Wegovy): For type 2 diabetes and weight management Tirzepatide (Mounjaro): A dual GIP/GLP-1 receptor agonist with significant weight loss effects Liraglutide (Saxenda): Approved specifically for weight management Dulaglutide (Trulicity): Primarily used for type 2 diabetes management Each medication has a unique dosing schedule and side effect profile that your healthcare provider can discuss during personalized consultations
Get this calculation wrong and you could inject two, five, or ten times your intended dose
Our bodies are designed to return to baseline, what we call homeostasis, after high-stress periods, Dr