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Research on Alzheimers disease models has demonstrated that hydrogen therapy can reduce cell apoptosis by modulating key apoptotic regulators such as Bax and caspase-3, thereby promoting neuronal survival ( In a neonatal rat hypoxicischemic brain injury (HIBI) model, hydrogen significantly reduced the Bax/Bcl-2 ratio by up-regulating the expression of the anti-apoptotic protein Bcl-2, while down-regulating the expression of the pro-apoptotic protein Bax and the apoptosis-executing enzyme caspase-3, leading to a reduction in apoptosis (Wang et al., 2020)

Based on the stubbornness and skin type, dermatologists may suggest combinational treatments for better results

doi:10.1039/c9fo00449a

It has been shown to increase weight loss and decrease fat mass

Mitochondria, which are structures within the cells of the RPE that act as energy powerhouses, are particularly susceptible to ROS-induced damage [17]