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The decline included both patients who could benefit from Seroquel and patients who could have been harmed by it, he said

While the risk is lower than at higher doses, it is still significantly higher than placebo (2%)

44 According to one study from 2019, which included 95 healthy volunteers, the tolerance was good at a single dose up to 3,000 g and in multiple doses up to 60 g without significant alterations of plasma lipids in healthy volunteers