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10.1152/ajpgi.00101.2011 Gastrointestinal Liver Physiol

Iron deficiency has been shown to decrease cholesterol-7a-hydroxylase activity, resulting in a decrease in bile salt secretion and favoring cholesterol crystal formation [30]

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It was identified in 1983 as a product of proglucagon conversion by L cells in the lining of the intestines and is also produced by pancreatic -cells, as well as being present in islet -cells and the intestine [82]