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In Alzheimers disease (AD) models, exercise improves cognitive impairment by increasing the amplitude and frequency of mEPSCs and mIPSCs in prefrontal cortical pyramidal neurons (Mu et al., 2022)

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Ipamorelin is the amplifier: it opens a second gate so the same GHRH drive translates into a bigger release, while its selectivity keeps cortisol and prolactin largely out of the picture

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When researchers knock out beta-catenin signaling in mice, the animals lose the ability to generate new hair follicles entirely

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