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The core mechanism of TB-500 is tissue regeneration through three pathways: angiogenesis (forming new blood vessels), cell migration (moving repair cells to the injury site), and anti-inflammatory action

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DMF/MMF actions may also be indirect, including blocking of cytokine-activated I-B, a cytoplasmic complex that can induce degradation of a NF-B inhibitor, releasing inflammatory transcription factors to the nucleus to induce inflammation