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By putting everything into context by describing the BBB structure, emphasizing how the barrier alters in age and disease, and the current drugs explored to slow the negative outcomes of age and disease through acting directly on the BBB, the goal is to exploit the easily accessible and manipulable microbiota as a potential target to modulate the BBB

Without adequate B12 intake, serious health problems can arise that often cannot be reversed

Recall that the most common yeast (SIFO) and SIBO symptoms are gas, bloating, and constipation

When adding tirzepatide to existing insulin therapy, consider an initial 10-20% reduction in basal insulin dose, with greater reductions (up to 20-30%) for patients with A1C levels near target