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The typical size range of these fibrinaloid microclots can allow them to travel widely through the vasculature, essentially blocking up capillaries of a suitable diameter, inhibiting blood flow and hence O 2 transfer to tissues, and thus accounting, in principle, for the very wide range of symptoms in syndromes such as long COVID, including fatigue [89], post-exertional symptom exacerbation [128], and autoantibody induction [38]

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Supplementary material The Supplementary Material for this article can be found online at: References 1 AllenJ

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This crucial interaction orchestrates neuronal differentiation, extensive dendritic branching, and heightened synaptic plasticity