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The lack of efficacy of inhaled GSH in patients with cystic fibrosis could be explained by the high concentrations of the GSH-degrading enzyme -glutamyltransferase present in lung fluids of those patients (116123), and then, the use of precursors of GSH synthesis like NAC and cystine could be more effective in the synthesis of GSH (124)

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This intensive approach suits short-term focused treatment phases

with the purpose of determining their antioxidant potency

After treatment with sample solutions of different volume fractions, the ROS content significantly decreased