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Sitagliptin is also a substrate of p-glycoprotein, which may also be involved in mediating the renal elimination of sitagliptin

That makes it a tool clinicians may consider when aiming to work with existing physiology

Para manejo de peso, opciones como naltrexona-bupropin, orlistat, fentermina-topiramato o fentermina (para uso a corto plazo) pueden considerarse, aunque generalmente con menor eficacia que los GLP-1

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While both Rybelsus (semaglutide pill) and Ozempic (semaglutide injection) are used in type-2 diabetes patients to improve glycemic control, these two medications are not the same, meaning, they are not interchangeable