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Chronic kidney disease (CKD) (e.g., FLOW), 3

453,454,455,456,457,458 Autophagy also enhances osteoclastogenesis through an overactive autophagy-lysosomal system, facilitating cartilage erosion and bone destruction

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Results from the phase 1 trial and open-label extension evaluating BIIB078 in adults with C9orf72 -ALS